Pearl Chiu

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Faculty, Department of Psychology
Clinical Science
Biological Psychology
Office Hours
By appointment
Office Address
Fralin Biomedical Research Institute at Virginia Tech Carilion
2 Riverside Circle
Roanoke, VA 24016
Office Phone
Curriculum Vitae
Short Bio
Current - Associate Professor, Virginia Tech Department of Psychology and Fralin Biomedical Research Institute at VT Carilion
2006-2007 Postdoctoral Fellow, Dept of Neuroscience, Baylor College of Medicine, Houston, TX
2006 PhD, Psychology (Clinical Science), Harvard University, Cambridge, MA
2005-2006 Clinical Psychology Internship, Adult Neuroscience Track, Baylor College of Medicine, Houston, TX
1998 AB, Psychology & Biology, Harvard University, Cambridge, MA
  • neuroscience of motivation and valuation, decision-making
  • depression, substance use disorders, PTSD and anxiety-related disorders
  • computational psychiatry
  • quantitative neurobehavioral predictors and mechanisms of treatment response
  • fMRI-informed assessment and intervention
  • interpersonal influences on decision-making

Select Publications
  • Brown, V, Zhu, L, Solway, A, Wang, JM, McCurry, KL, King-Casas, B, Chiu, PH (2021). Reinforcement Learning Disruptions in Individuals With Depression and Sensitivity to Symptom Change Following Cognitive Behavioral Therapy. JAMA psychiatry, e211844. Advance online publication.
  • Chung, D, Orloff, M, Lauharatanahirun, N, Chiu, PH, King-Casas, B (2020) Valuation of peers’ safe choices is associated with substance-naïveté in adolescents. Proceedings of the National Academy of Sciences, USA, 117, 31729-31737.
  • McCurry KL, Frueh BC, Chiu PH, King-Casas B. (2020) Opponent effects of hyperarousal and re-experiencing on affective habituation in posttraumatic stress disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5, 203-212.
  • Wang, JM, Zhu, L, Brown, VM, De La Garza II, R, Newton, T, King-Casas, B, Chiu, PH (2019) In cocaine dependence, neural prediction errors during loss avoidance are increased with cocaine deprivation and predict drug use. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 291-299.
  • Brown, VM, Zhu, L, Wang, JM, Frueh, BC, King-Casas, B, Chiu, PH (2018). Associability-modulated loss learning is increased in posttraumatic stress disorder. eLife 2018; 7:e30150.
  • Chung, D, Kadlec, K, Aimone, JA, McCurry, K, King-Casas, B, Chiu, PH (2017). Valuation in major depression is intact and stable in a non-learning environment. Scientific Reports, 7, 44374.
  • Chung, D, Christopoulos, G, King-Casas, B, Ball, S, Chiu, PH (2015). Social signals of safety and risk confer utility and have asymmetric effects on observers’ choices. Nature Neuroscience, 18, 912 - 916.
  • Williams, W, Graham, D, McCurry, K, Sanders, A, Eiseman, J, Chiu, PH, King-Casas, B (2014). Group psychotherapy’s impact on trust in veterans with PTSD: A pilot study. Bulletin of the Menninger Clinic, 78, 335 - 348.
  • Marsden, KE, Ma WJ, Deci EL, Ryan RM, Chiu PH (2014) Diminished neural responses predict enhanced intrinsic motivation and sensitivity to external incentive. Cognitive, Affective, and Behavioral Neuroscience, 15, 276 - 286.
  • Zhu, L, Jenkins, AC, Set, E, Scabini, D, Knight, RT, Chiu, PH, King-Casas, B, Hsu, M (2014). Damage to dorsolateral prefrontal cortex affects tradeoffs between honesty and self-interest. Nature Neuroscience, 17, 1319-1321.
  • King-Casas, B & Chiu, PH (2012). Understanding interpersonal function in psychiatric illness through multiplayer economic games. Biological Psychiatry, 72, 119-125.
  • Lindsey, L, King-Casas, B, Brovko, J, Chiu, PH (2009). Toward functional neurobehavioral assessment of mood and anxiety. Conf Proc IEEE Engineering in Medicine and Biology Society, 2009, 5393-5396.
  • Chiu, PH, Kayali, MA, Kishida, KT, Tomlin, D, Klinger, LG, Klinger, MR, Montague, PR (2008). Self responses along cingulate cortex reveal quantitative neural phenotype for high functioning autism. Neuron, 57, 463-473.
  • Chiu, PH, Lohrenz, TM, Montague, PR (2008). Smokers’ brains compute but ignore a fictive error signal in a sequential investment task. Nature Neuroscience, 11, 514-520.
  • Chiu, PH, Holmes, AJ, Pizzagalli, DA (2008). Dissociable recruitment of rostral anterior cingulate and inferior frontal cortex in emotional response inhibition. NeuroImage, 42, 988-997.
  • Chiu, PH & Deldin, P (2007). Neural evidence for enhanced error detection in major depressive disorder. American Journal of Psychiatry, 164, 608-616.
  • Deldin, P & Chiu, P (2005). Cognitive restructuring and EEG in major depression. Biological Psychology, 70, 141-151.