Pearl Chiu

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Professor
Patricia Caldwell Faculty Fellow
Department of Psychology (Clinical Science; Cognitive Neuroscience & Biopsychology)
Fralin Biomedical Research Institute at Virginia Tech Carilion
EMail
Office Hours
By appointment.


***For Fall 2026 entry, Dr. Chiu's lab has limited openings for doctoral applicants in Psychology. Exceptions may be made for individuals who have demonstrated exceptional aptitude for research. Applicants interested in Dr. Chiu's lab may also consider VT's doctoral programs in Neuroscience or Translational Biology, Medicine, and Health. Please include CV with inquiries.***

Office Address
Fralin Biomedical Research Institute at Virginia Tech Carilion
2 Riverside Circle
Roanoke, VA 24016
Office Phone
Curriculum Vitae
Short Bio
Current - Professor, Virginia Tech Department of Psychology and Fralin Biomedical Research Institute at VT Carilion
2006-2007 Postdoctoral Fellow, Dept of Neuroscience, Baylor College of Medicine, Houston, TX
2006 PhD, Psychology (Clinical Science), Harvard University, Cambridge, MA
2005-2006 Clinical Psychology Internship, Adult Neuroscience Track, Baylor College of Medicine, Houston, TX
1998 AB, Psychology & Biology, Harvard University, Cambridge, MA
Interests
  • neuroscience of motivation and valuation, decision-making
  • depression, substance use disorders, anxiety-related disorders
  • computational psychiatry
  • neuroscience-informed assessment and intervention
  • interpersonal influences on decision-making

Select Publications
  • Bansal, V, McCurry, KL, Lisinski, J, Kim, D-Y, Goyal, S, Wang, JM, Lee, J, Brown, VM, LaConte SM, Casas, B, Chiu, PH (2025) Reinforcement learning processes as forecasters of depression remission. Journal of Affective Disorders, 368, 829–837.
  • Orloff, M, Chung, D, Gu, X, Wang, X, Gao, Z, Song, G, Tatineni, C, Xu, S, Casas, B, Chiu, PH (2024). Social conformity is a heuristic when individual risky decision-making is disrupted. PLOS Computational Biology, 20, e1012602.
  • Kim, D-Y, Lisinski, J, Caton, M, Casas, B, LaConte, S, Chiu, PH (2024) Regulation of craving for real-time fMRI neurofeedback based on individual classification. Philosophical Transactions of the Royal Society B. 379:20230094.
  • Brown, VM, Lee, J, Wang, JM, Casas, B, Chiu, PH (2024) Reinforcement learning-informed queries guide behavioral change. Clinical Psychological Science, 126, 1146 - 1161.
  • Brown, V, Zhu, L, Solway, A, Wang, JM, McCurry, KL, King-Casas, B, Chiu, PH (2021). Reinforcement learning disruptions in individuals with depression and sensitivity to symptom change following cognitive behavioral therapy. JAMA Psychiatry, 78, 1113-1122.
  • Chung, D, Orloff, M, Lauharatanahirun, N, Chiu, PH, King-Casas, B (2020) Valuation of peers’ safe choices is associated with substance-naïveté in adolescents. Proceedings of the National Academy of Sciences, USA, 117, 31729-31737.
  • McCurry KL, Frueh BC, Chiu PH, King-Casas B. (2020) Opponent effects of hyperarousal and re-experiencing on affective habituation in posttraumatic stress disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5, 203-212.
  • Wang, JM, Zhu, L, Brown, VM, De La Garza II, R, Newton, T, King-Casas, B, Chiu, PH (2019) In cocaine dependence, neural prediction errors during loss avoidance are increased with cocaine deprivation and predict drug use. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 291-299.
  • Brown, VM, Zhu, L, Wang, JM, Frueh, BC, King-Casas, B, Chiu, PH (2018). Associability-modulated loss learning is increased in posttraumatic stress disorder. eLife 2018; 7:e30150.
  • Chung, D, Kadlec, K, Aimone, JA, McCurry, K, King-Casas, B, Chiu, PH (2017). Valuation in major depression is intact and stable in a non-learning environment. Scientific Reports, 7, 44374.
  • Chung, D, Christopoulos, G, King-Casas, B, Ball, S, Chiu, PH (2015). Social signals of safety and risk confer utility and have asymmetric effects on observers’ choices. Nature Neuroscience, 18, 912 - 916.
  • Marsden, KE, Ma WJ, Deci EL, Ryan RM, Chiu PH (2014) Diminished neural responses predict enhanced intrinsic motivation and sensitivity to external incentive. Cognitive, Affective, and Behavioral Neuroscience, 15, 276 - 286.
  • King-Casas, B & Chiu, PH (2012). Understanding interpersonal function in psychiatric illness through multiplayer economic games. Biological Psychiatry, 72, 119-125.
  • Chiu, PH, Lohrenz, TM, Montague, PR (2008). Smokers’ brains compute but ignore a fictive error signal in a sequential investment task. Nature Neuroscience, 11, 514-520.
  • Chiu, PH, Holmes, AJ, Pizzagalli, DA (2008). Dissociable recruitment of rostral anterior cingulate and inferior frontal cortex in emotional response inhibition. NeuroImage, 42, 988-997.
  • Chiu, PH & Deldin, P (2007). Neural evidence for enhanced error detection in major depressive disorder. American Journal of Psychiatry, 164, 608-616.