Pearl Chiu

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Patricia Caldwell Faculty Fellow
Department of Psychology (Clinical Science; Cognitive Neuroscience & Biopsychology)
Fralin Biomedical Research Institute at Virginia Tech Carilion
Office Hours
By appointment.

**We expect to have limited spots for doctoral program applicants for Fall 2025. Exceptions may be made for individuals from underrepresented groups and/or with disadvantaged backgrounds and/or who have demonstrated exceptional motivation for research. Quantitative aptitude and programming experience will be considered favorably. Please include CV with inquiries.
Office Address
Fralin Biomedical Research Institute at Virginia Tech Carilion
2 Riverside Circle
Roanoke, VA 24016
Office Phone
Short Bio
Current - Professor, Virginia Tech Department of Psychology and Fralin Biomedical Research Institute at VT Carilion
2006-2007 Postdoctoral Fellow, Dept of Neuroscience, Baylor College of Medicine, Houston, TX
2006 PhD, Psychology (Clinical Science), Harvard University, Cambridge, MA
2005-2006 Clinical Psychology Internship, Adult Neuroscience Track, Baylor College of Medicine, Houston, TX
1998 AB, Psychology & Biology, Harvard University, Cambridge, MA
  • neuroscience of motivation and valuation, decision-making
  • depression, substance use disorders, anxiety-related disorders
  • computational psychiatry
  • neuroscience-informed assessment and intervention
  • interpersonal influences on decision-making

Select Publications
  • Brown, VM, Lee, J, Wang, JM, Casas, B, Chiu, PH (2024) Reinforcement learning-informed queries guide behavioral change. Clinical Psychological Science. Online ahead of print.
  • Brown, V, Zhu, L, Solway, A, Wang, JM, McCurry, KL, King-Casas, B, Chiu, PH (2021). Reinforcement learning disruptions in individuals with depression and sensitivity to symptom change following cognitive behavioral therapy. JAMA Psychiatry, 78, 1113-1122.
  • Chung, D, Orloff, M, Lauharatanahirun, N, Chiu, PH, King-Casas, B (2020) Valuation of peers’ safe choices is associated with substance-naïveté in adolescents. Proceedings of the National Academy of Sciences, USA, 117, 31729-31737.
  • McCurry KL, Frueh BC, Chiu PH, King-Casas B. (2020) Opponent effects of hyperarousal and re-experiencing on affective habituation in posttraumatic stress disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5, 203-212.
  • Wang, JM, Zhu, L, Brown, VM, De La Garza II, R, Newton, T, King-Casas, B, Chiu, PH (2019) In cocaine dependence, neural prediction errors during loss avoidance are increased with cocaine deprivation and predict drug use. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 291-299.
  • Brown, VM, Zhu, L, Wang, JM, Frueh, BC, King-Casas, B, Chiu, PH (2018). Associability-modulated loss learning is increased in posttraumatic stress disorder. eLife 2018; 7:e30150.
  • Chung, D, Kadlec, K, Aimone, JA, McCurry, K, King-Casas, B, Chiu, PH (2017). Valuation in major depression is intact and stable in a non-learning environment. Scientific Reports, 7, 44374.
  • Chung, D, Christopoulos, G, King-Casas, B, Ball, S, Chiu, PH (2015). Social signals of safety and risk confer utility and have asymmetric effects on observers’ choices. Nature Neuroscience, 18, 912 - 916.
  • Williams, W, Graham, D, McCurry, K, Sanders, A, Eiseman, J, Chiu, PH, King-Casas, B (2014). Group psychotherapy’s impact on trust in veterans with PTSD: A pilot study. Bulletin of the Menninger Clinic, 78, 335 - 348.
  • Marsden, KE, Ma WJ, Deci EL, Ryan RM, Chiu PH (2014) Diminished neural responses predict enhanced intrinsic motivation and sensitivity to external incentive. Cognitive, Affective, and Behavioral Neuroscience, 15, 276 - 286.
  • Zhu, L, Jenkins, AC, Set, E, Scabini, D, Knight, RT, Chiu, PH, King-Casas, B, Hsu, M (2014). Damage to dorsolateral prefrontal cortex affects tradeoffs between honesty and self-interest. Nature Neuroscience, 17, 1319-1321.
  • King-Casas, B & Chiu, PH (2012). Understanding interpersonal function in psychiatric illness through multiplayer economic games. Biological Psychiatry, 72, 119-125.
  • Chiu, PH, Kayali, MA, Kishida, KT, Tomlin, D, Klinger, LG, Klinger, MR, Montague, PR (2008). Self responses along cingulate cortex reveal quantitative neural phenotype for high functioning autism. Neuron, 57, 463-473.
  • Chiu, PH, Lohrenz, TM, Montague, PR (2008). Smokers’ brains compute but ignore a fictive error signal in a sequential investment task. Nature Neuroscience, 11, 514-520.
  • Chiu, PH, Holmes, AJ, Pizzagalli, DA (2008). Dissociable recruitment of rostral anterior cingulate and inferior frontal cortex in emotional response inhibition. NeuroImage, 42, 988-997.
  • Chiu, PH & Deldin, P (2007). Neural evidence for enhanced error detection in major depressive disorder. American Journal of Psychiatry, 164, 608-616.